Further Exploring the Antibacterial Properties of Endophytic Metabolites Found in Oenothera biennis 

Presenter

Edward AF Urkowitz

Campus

Salem State University

Sponsor

Christine MacTaylor, Department of Chemistry and Physics, Salem State University

Schedule

Session 3, 1:30 PM - 2:15 PM [Schedule by Time][Poster Grid for Time/Location]

Location

Poster Board A56, Campus Center Auditorium, Row 3 (A41-A60) [Poster Location Map]

Abstract

In the search for novel treatments for evolving health issues, endophytes represent an exciting new frontier in research. The fungal endophytes found in plants show untapped potential in the development of new antibacterial treatments. In this study, fungal endophytes from Oenothera biennis [evening primrose] were extracted and analyzed for potential medical applications. The endophytes were cultivated for their metabolites which were extracted from the endophytic growth media. These metabolites were then purified and analyzed using LCMS (Liquid Chromatography Mass Spectrometry). The analysis revealed a wide array of chemical compounds with known uses in the pharmaceutical industry. In addition, the purified metabolites were tested for antibacterial properties against Staphylococcus aureus, Staphylococcus epidermidis, Vibrio Parahaemolyticus, Pseudomonas Aeruginosa and Escherichia coli. Only Staphylococcus aureus and Escherichia coli showed any signs of inhibition. Results between the two methods yielded inconsistent results. Because of these inconsistencies, further research is currently ongoing to retest these methods. Results found from this retest will be compared with the results found in the prior tests and presented. 

Keywords

Antibacterials, Pharmaceutical, LCMS analysis, Botany, Chemical Engineering

Research Area

Chemistry and Materials Science

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