Comparative Analysis of Malaria Vaccines: A Literature Review 

Presenter

Veronica Blythe Shalom Grubb

Campus

Mount Wachusett Community College

Sponsor

Daniel Soucy, Department of Philosophy, Mount Wachusett Community College

Schedule

Session 4, 2:30 PM - 3:15 PM [Schedule by Time][Poster Grid for Time/Location]

Location

Poster Board C9, Poster Showcase Room (163), Row 1 (C1-C10) [Poster Location Map]

Abstract

This research paper focuses on the various attempts at developing a vaccine for malaria over time. Some background on malaria and various Plasmodium species (in particular P. falciparum) will be discussed, as well as the history of malaria treatment, with a focus on comparing different malaria vaccines that have been developed (including GlaxoSmithKline's RTS,S/AS01 and the University of Oxford’s R21/Matrix-M), and current research being done on potential new vaccines. By reviewing and summarizing research from scientific and medical journals, this research paper will inform the layperson on the need for malaria vaccines, the challenges with vaccination against Plasmodium, and the progress being made. The goal is to educate and spread awareness, as malaria is the leading cause of death in many developing nations, especially for young children. According to the CDC, malaria killed an estimated 627,000 people worldwide in 2020. An effective and widely available malaria vaccine will change the world, and while vaccine research has come a long way, there are still some improvements to be made. This will save innumerable lives and would be one of the greatest advancements in public health in all of human history, so it is imperative that governments fund vaccine research and distribution.

Keywords

Malaria, Vaccines, Infectious disease, Tropical medicine, Plasmodium

Research Area

Disease Detection, Prevention & Treatment

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