The Possible Association between Mirena Use and Increased Risk of Symptoms at Midlife

Presenter

Ava Grace Warner

Campus

UMass Amherst

Sponsor

Lynnette Leidy Sievert, Department of Anthropology, UMass Amherst

Schedule

Session 4, 2:30 PM - 3:15 PM [Schedule by Time][Poster Grid for Time/Location]

Location

Poster Board A81, Campus Center Auditorium, Row 5 (A81-A100) [Poster Location Map]

Abstract

Mirena is a 52mg levonorgestrel-releasing intrauterine system. Levonorgestrel is a synthetic progestogen similar to progesterone, which allows Mirena to offer long-acting contraception at a low hormonal rate. It was originally introduced in 1990 to reduce the adverse effects of copper IUDs, and is currently available in more than 120 countries. Mirena is prescribed at midlife for treatment of heavy menstrual bleeding and excessive blood loss. The Mirena IUD is therefore specifically focused on in this study to examine the possible association between Mirena use and the increased risk of symptoms at midlife. Analysis for this study was done using both bivariate and logistic regression analysis. Data were drawn from the Brown Adipose Tissue and Hot Flash study (n=274, women aged 45-55) conducted at UMass Amherst. Preliminary results indicate no significant relationships between the use of Mirena and any of the four major symptom categories; vasomotor symptoms (hot flashes, p= 0.526, and night sweats, p= 0.448); psychological symptoms (feeling depressed, p= 0.714, and mood swings, p= 0.963); physical symptoms (aches/stiffness in joints, p= 0.952, backaches, p= 0.243, and leg cramps, p= 0.631); and psychosexual symptoms (loss of sexual desire, p= 0.542. and vaginal dryness, p= 0.869). These findings reassure women that use of the Mirena IUD for treatment of heavy blood loss is unlikely to have adverse effects on symptoms at midlife.

Keywords

Menopause, Contraception, Women's Health

Research Area

Medical Sciences

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