Long-Term Effects of Benzodiazepines on the Brain

Presenter

Tabarek Al Bakri

Campus

Springfield Technical Community College

Sponsor

Reena Randhir, Department of Biology, Springfield Technical Community College

Schedule

Session 4, 2:30 PM - 3:15 PM [Schedule by Time][Poster Grid for Time/Location]

Location

Poster Board A83, Campus Center Auditorium, Row 5 (A81-A100) [Poster Location Map]

Abstract

Benzodiazepines are effective psychoactive medicines that has a depressant effect on the nerves and is prescribed for sedation, insomnia, anxiety, and muscle relaxation. But its long term use can cause dependency, and addiction. It is commonly called Valium or Xanax and its mode of action is by affects gamma aminobutyric acid (GABA) neurotransmitters. The objective of this research is to decipher the effects of long-term benzodiazepine use on the brain by a systematic literature review. Recently the U.S. Food and Drug Administration also announced the risk of misuse and dependence associated with this drug. Hence further research is required to manage the long-term consequences for patients dependent on benzodiazepines and facing memory loss or impairment of motor functions. Patient MRI scans and testing indicate anatomical and molecular changes in the brain with prolonged usage. The main way that benzodiazepines can affect your brain is by damaging your GABA receptors by making them downregulate and desensitize the receptors. In conclusion, I advocate for research focus to understand how this drug can be used judiciously for patient longevity with minimal neurophysiological effects. Patients should be taught about the potential side effects, while healthcare providers should explore alternative and tailored treatments for optimal health.

Keywords

Cognitive damage , Mental problems , Over usage drugs

Research Area

Medical Sciences

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