Exploring the Interaction Similarities between IGF-1 and Insulin-Binding to the Insulin Receptor

Presenter

Taylor R. Camossi

Group Members

Sultan Ahmed Abbas Hussein

Campus

Westfield State University

Sponsor

Roderico Acevedo, Department of Chemical and Physical Sciences, Westfield State University

Schedule

Session 4, 2:30 PM - 3:15 PM [Schedule by Time][Poster Grid for Time/Location]

Location

Poster Board A84, Campus Center Auditorium, Row 5 (A81-A100) [Poster Location Map]

Abstract

The main role of the insulin receptor is to facilitate the cellular uptake of glucose in response to insulin binding. Insulin is a peptide hormone produced by the pancreas. Another peptide hormone, Insulin-like Growth Factor 1 (IGF-1) which is primarily produced in liver can also interact with the insulin receptor.  Here, we will use the 3D virtual reality application, Nanome, to visually explore the interface landscape of both peptide hormones with the insulin receptor, taking special note of the noncovalent interactions that create the interface. By using virtual reality technology, students can experience the volume of proteins and their interactions. Use of this technology can deepen student understanding of biomolecular processes.

Keywords

Virtual Reality , IGF-1, Insulin, Receptors, Interactions

Research Area

Medical Sciences

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