Genetic Risk Factors and Preventative Strategies for Breast Cancer

Presenter

Renae S. Fraser

Campus

Springfield Technical Community College

Sponsor

Reena Randhir, Department of Biology, Springfield Technical Community College

Schedule

Session 4, 2:30 PM - 3:15 PM [Schedule by Time][Poster Grid for Time/Location]

Location

Poster Board C12, Poster Showcase Room (163), Row 2 (C11-C20) [Poster Location Map]

Abstract

Cancer is the second leading cause of death in the world. Regarding breast cancer, a person’s genetics is responsible for 5-10% but with changes or mutations in the BRCA (BReast CAncer) 1 or 2 gene the risk is increased to 80%. These genes make tumor suppressor proteins that play a role in the normal regulation of the cell cycle. This study explains the risk factors of cancer due to this and some preventative measures. Methods include a review of the scientific literature from PubMed and Google Scholar. The findings confirmed that these gene mutations, environmental toxins and lifestyle are responsible for the development of breast cancer. Data from National Institute of Health indicates that diet, obesity, smoking, hormonal imbalance, insulin resistance and physical inactivity, may increase the risk of breast and ovarian cancer. The review also indicates the need for better ways for early detection, assessment of family medical history, and to develop individualized treatment plans to prevent or manage this cancer. There is an urgent need for increased vigilance by our physicians to identify at-risk individuals and implement tailored treatments for breast and ovarian cancer.

Keywords

BRCA1, BRCA2, mutations, disease, risk factors

Research Area

Disease Detection, Prevention & Treatment

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